ANTICOV, the largest COVID-19 clinical trial to date in Africa, was launched by the public-private partnership Drugs for Neglected Diseases initiative (DNDi). ITM, together with thirteen African countries and an international network of research institutions, will test repurposed medications for mild and moderate cases of COVID-19 in the hope of preventing hospitalisation for those afflicted. The clinical trial is being carried out at 19 sites in 13 countries and is funded by UnitAid. ITM will also conduct ancillary studies on household transmission and on immunology of SARS-CoV-2 in six countries.